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Research Call

DAFM Reference


DAFM Award

DAFM National Call 2013 13F492 TCD €198,780

Project Title:

The Irish Longitudinal Ageing Study (TILDA) Nutritional Biomarker Database Enhancement Initiative

Project Coordinator:

Dr Anne Molloy

Project Abstract

In the first wave of recruitment into the Irish Longitudinal Study on Ageing (TILDA), bloods were collected and stored from approximately 5000 people aged 50+. No funding was provided for blood biomarker analysis and so samples were stored at -80°C for future analysis of metabolites that are important determinants of healthy ageing. The present proposal will deliver baseline blood concentration data into the TILDA database for three micronutrients and an inflammation marker that are highly relevant to ageing and age related social policy – folate, vitamin B12, vitamin D and C-reactive protein 9crp). Low status of the three vitamins has been associated with multiple adverse health outcomes in older persons in both prospective and case control studies. This project will allow the prevalence of inadequate status of these micronutrients to be assessed on this unique national cohort and the relationship between inadequate status and adverse health conditions, including inflammation, to be explored. The data will also provide an invaluable resource for prospective studies in the later waves of this longitudinal study and will provide evidence for policy makers and the food industry in relation to future policies for food fortification and disease prevention.

Final Report: